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Change & defence

HHorizontal gene transfer

Sideways DNA traffic — conjugation, transduction, transformation as names and history, not protocols.

Also called: Lateral gene transfer · Mobile DNA

Diagram of DNA moving between bacterial cells
Andrew Z. Colvin · CC BY-SA 4.0
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1928 Griffith effect19281944 DNA is the principle19441946 Conjugation shown19461952 Transduction named19521959 Plasmid word19591970s R-plasmids clinical1970s1989 Integron described19892008-10s NDM tours2008-10s
  1. Griffith effect
  2. DNA is the principle
  3. Conjugation shown
  4. Transduction named
  5. Plasmid word
  6. R-plasmids clinical
  7. Integron described
  8. NDM tours
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14 min read

Last reviewed Sources & creditsMedia creditsMethodology

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Quick facts

Fred Griffith showed that a 'transforming principle' from heat-killed smooth pneumococci could change live rough cells in mice — history, not a protocol.Griffith 1928
Avery, MacLeod and McCarty identified the transforming principle as DNA, a foundation of molecular biology.Avery 1944
Lederberg and Tatum showed E. coli can exchange genes by direct contact — conjugation in the textbook sense.Conjugation 1946
Zinder and Lederberg found phages can ferry bacterial genes between cells.Transduction 1952
Beta-lactamase and other cassettes ride plasmids and integrons across species — why stewardship is ecological.Resistance hitchhikers
Transformation, conjugation and transduction are the named routes. This page stays at names and history, not lab steps.Three textbook routes

Horizontal gene transfer is sideways inheritance: DNA moves between contemporaries instead of only from parent to offspring.

That is why resistance genes can jump species in hospitals and farms. The public story is traffic, not a construction kit.

Transformation, conjugation and transduction are names for different vehicles. None of them is written here as a protocol.

45FamiliarityEditorial 0–100 browsing aid within this atlas.
55Medical weightEditorial 0–100 browsing aid within this atlas.
25BenefitEditorial 0–100 browsing aid within this atlas.
50RiskEditorial 0–100 browsing aid within this atlas.

Horizontal gene transfer — concrete atlas depth on Tool-Lifes.

Best-of microbe rankings

Horizontal gene transfer — concrete atlas depth on Tool-Lifes.

Local lens

Genes that travel sideways

English biology class taught a tree. Resistance news taught a web: plasmids moving between species.

Plasmid in news

A ring of DNA that can move. Not a moral actor.

Species walls

They leak. That is why stewardship is ecological.

Public-health desks

No transformation recipes. Educational only.

Read the local lens — English-speaking public health

The profile

455525508240
  • Familiarity45
  • Medical weight55
  • Benefit25
  • Risk50
  • Research82
  • Live debate40

Risk

50 / 100

Sideways DNA traffic — conjugation, transduction, transformation as names and history, not protocols.

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Frequently asked questions

Where should I start with Horizontal gene transfer?
Read Identity → How they live → Body & health, then use compare rails.
Is this page advice for Horizontal gene transfer?
Public-health education — not a care plan, prescription, or outbreak briefing.
What does the local lens add?
It names everyday desks for Change & defence before English norms look universal.
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No — editorial 0–100 browsing aids inside this atlas only.
How do I compare Horizontal gene transfer to neighbours?
Use related cards and best-of / quiz rails after the first three chapters.
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How they live and Body & health carry mechanisms; skim Identity first.
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Primary desks for Change & defence: public-health desks and lab teaching frames.

Sources & research

  1. Horizontal gene transfer2026 · Wikipedia
  2. Griffith's experiment2026 · Wikipedia

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